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Hamilton RJ et al. – In this cohort of men undergoing RP, statin use was associated with a dose-dependent reduction in the risk of biochemical recurrence. If confirmed in other studies, these findings suggest statins may slow PC progression after R
Methods
Many randomised controlled trials have investigated the effect of adjuvant chemotherapy in operable non-small-cell lung cancer. We undertook two comprehensive systematic reviews and meta-analyses to establish the effects of adding adjuvant chemotherapy to surgery, or to surgery plus radiotherapy. The addition of adjuvant chemotherapy after surgery for patients with operable non-small-cell lung cancer improves survival.
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1 Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: Two meta-analyses of individual patient data - 100% The Lancet, June 10, 2010
2 Adjuvant chemotherapy use and adverse events among older patients with stage III colon cancer - 96% JAMA, May 14, 2010
3 Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: Two meta-analyses of individual patient data - 96% The Lancet - Early Online Publication, May 21, 2010
4 Treatment results of FOLFOX chemotherapy before surgery for lymph node metastasis of advanced colorectal cancer with synchronous liver metastasis: the status of LN metastasis and vessel invasions at the primary site in patients who responded to FOLFOX - 92% International Journal of Clinical Oncology, March 28, 2010
5 Sequential chemotherapy and intensity-modulated radiation therapy in the management of locoregionally advanced nasopharyngeal carcinoma: Experience of 370 consecutive cases - 90% BMC Cancer, April 16, 2010
6 Changes in markers of ovarian reserve and endocrine function in young women with breast cancer undergoing adjuvant chemotherapy - 81% Cancer, April 28, 2010
7 Clinicopathological variables predictive of clinical outcome in patients with figo stage IB2-IIb cervical cancer treated with cisplatin-based neoadjuvant chemotherapy followed by radical hysterectomy - 78% Anticancer Research, April 16, 2010
8 Pancreatic proteolytic enzyme therapy compared with gemcitabine-based chemotherapy for the treatment of pancreatic cancer - 77% Journal of Clinical Oncology, May 7, 2010
9 Surgery with or without preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer: Southwest Oncology Group Trial s9900, an intergroup, randomized, phase III trial - 77% Journal of Clinical Oncology, May 15, 2010
10 Neoadjuvant chemotherapy plus surgery versus surgery for cervical cancer - 73% Cochrane Reviews, April 2, 2010
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